Sangi Apadent Total Care is a Japanese toothpaste containing medical nano-HAP.
This component repairs the enamel and protects against periodontal diseases such gingivitis and sensitivity.
Has a mild mint flavor.
Nano Medical HAP (nano<mHAP>) is a proprietary form of the calcium phosphate compound calcium apatite, originally developed by Sangi and clinically approved as an anti-caries ingredient in Japan in 1993.
Nano<mHAP> is almost the same substance as the HAP of our teeth thus it is safe, biocompatible and even edible!
Nano<mHAP> protects and restores tooth enamel in 3 ways:
- Collecting and helping to remove plaque: its nanoparticles bind protein such as oral bacteria and plaque fragments during brushing, facilitating their removal from the mouth.
- Filling surface fissures: the crystalline calcium phosphate nanoparticles directly replace lost mineral to restore subsurface demineralized areas of tooth enamel (incipient caries) and fill microscopic fissures on the enamel surface.
- Remineralizing subsurface demineralized areas (incipient caries): it directly replaces lost mineral to restore subsurface demineralized areas of tooth enamel (incipient caries).
Finally it also relieves tooth sensitivity by filling and coating exposed dentin tubules.
- Net contents: 50g
- Made in Japan
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Large selection of curated, high-quality products
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Most affordable prices in the market
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Rapid shipping, no matter the location
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In-house customer service by phone, chat or email
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Loyalty program & membership benefits
- TKTeshera K.Verified BuyerReviewingSangi Apadent Total Care Protective Remineralizing Toothpaste 100gI recommend this productRated 5 out of 5 stars4/10/25Best Toothpaste!
this is the best toothpaste I have ever tried that actually helps my teeth feel healthy and clean!
- VPVal P.Verified BuyerReviewingSangi Apadent Total Care Protective Remineralizing Toothpaste 100gI recommend this productRated 5 out of 5 stars3/27/25Great
I’ve purchased this toothpaste twice and will continue to buy it. Effective with a nice taste. Recommended!
- FZFEDIR Z.Verified BuyerReviewingSangi Apadent Total Care Protective Remineralizing Toothpaste 100gI recommend this productRated 5 out of 5 stars2/15/25Beautiful!
Using this toothpaste you will prevent those trips to the dentist that can cost you thousands of dollars
- IPIrina P.Verified BuyerReviewingSangi Apadent Total Care Protective Remineralizing Toothpaste 100gI recommend this productRated 5 out of 5 stars2/5/25Irina
best toothpaste
- ASAnna S.Verified BuyerReviewingSangi Apadent Total Care Protective Remineralizing Toothpaste 100gI recommend this productRated 5 out of 5 stars2/4/25toothpaste that saved my enamel
I've been using this toothpaste for years after my dentist recommended it because my teeth were really sensitive. I use a different toothpaste in the morning and switch to this one at night before bed. I also get my teeth professionally remineralised once a year by my hygienist (using the Apadent product too). Now, my teeth aren’t sensitive anymore—I don’t get any reactions to sweets or hot and cold drinks. I honestly think this is the best product for fixing this problem.
- NLnhat lynh h.Verified BuyerReviewingSangi Apadent Total Care Protective Remineralizing Toothpaste 100gI recommend this productRated 5 out of 5 stars1/18/25Toothpaste
I hooked on this
Mild mint and feel fresh
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